A histopathologic study of gastric and small intestinal graft-versus-host disease following allogeneic bone marrow transplantation

DC Snover, SA Weisdorf, GM Vercellotti, B Rank… - Human pathology, 1985 - Elsevier
Twenty-two stomach and 14 small intestinal biopsy specimens from 24 allogeneic bone
marrow transplant recipients were reviewed to evaluate the histopathologic changes of graft-
versus-host disease (GVHD) in these organs. Associations between these results and
clinical symptoms and other biopsy results were sought. In both organs, single epithelial cell
necrosis was found to correlate with GVHD. Gastric GVHD was diagnosed in eight patients
and small intestinal GVHD in four. Gastric GVHD was characterized by nausea, vomiting …