In vivo incidence of apoptosis evaluated with the TdT FragEL™ DNA fragmentation detection kit in cartilage and bone cells of the rat tibia
G Silvestrini, P Mocetti, P Ballanti, R Di Grezia… - Tissue and Cell, 1998 - Elsevier
Previous studies have shown the occurrence of cell death by apoptosis in cartilage and
bone cells, and have suggested a functional relationship between bone growth and
remodelling on one hand, and numbers of apoptotic cells on the other. At present, no in vivo
studies are available on the frequency of the apoptotic process measured at one time and in
one place using the cartilage and bone cells of single specimens. The aim of the present
investigation was to measure the in vivo incidence of apoptosis in cartilage and bone cells of …
bone cells, and have suggested a functional relationship between bone growth and
remodelling on one hand, and numbers of apoptotic cells on the other. At present, no in vivo
studies are available on the frequency of the apoptotic process measured at one time and in
one place using the cartilage and bone cells of single specimens. The aim of the present
investigation was to measure the in vivo incidence of apoptosis in cartilage and bone cells of …