Serological evidence of past hepatitis B infection in liver donor and hepatitis B infection in liver allograft

JA Lowell, TK Howard, S Shenoy, HM White… - The Lancet, 1995 - Elsevier
JA Lowell, TK Howard, S Shenoy, HM White, DC Brennan, MG Peters, PC Huettner
The Lancet, 1995Elsevier
The presence of hepatitis B surface and core antibodies (anti-HBs and anti-HBc) in a liver
donor without hepatitis B surface antigen is taken to indicate resolution of hepatitis B and is
not considered to contraindicate donation. We report a liver transplant recipient who
developed hepatitis B after such a donation. It seems that hepatitis B virus can reside in the
liver of a patient who has seemingly recovered from his disease. We recommend avoidance
of liver transplants from donors who are positive for anti-HBs and anti-HBc.
The presence of hepatitis B surface and core antibodies (anti-HBs and anti-HBc) in a liver donor without hepatitis B surface antigen is taken to indicate resolution of hepatitis B and is not considered to contraindicate donation. We report a liver transplant recipient who developed hepatitis B after such a donation. It seems that hepatitis B virus can reside in the liver of a patient who has seemingly recovered from his disease. We recommend avoidance of liver transplants from donors who are positive for anti-HBs and anti-HBc.
Elsevier