Evaluation of monoclonal antibodies with specificity of human IgA, IgA subclasses and allotypes and secretory component results of an IUIS/WHO collaborative study
J Mestecky, RG Hamilton, CGM Magnusson… - Journal of …, 1996 - Elsevier
51 monoclonal antibodies (McAb) with putative specificity for human IgA, the IgA subclasses,
Am allotypes or secretory component (SC) were evaluated for immunoreactivity and
specificity by nine laboratories employing immunodiffusion, agglutination,
immunohistological assays, immunoblotting and direct binding and competitive inhibition
enzyme immunoassays. McAbs specific for IgA PAN (n= 24), IgA1 (n= 7), IgA2 (n= 3), IgA2m
(2)(n= 2), non-IgA2m (2)(n= 4) and SC or secretory IgA (n= 5) were identified that were …
Am allotypes or secretory component (SC) were evaluated for immunoreactivity and
specificity by nine laboratories employing immunodiffusion, agglutination,
immunohistological assays, immunoblotting and direct binding and competitive inhibition
enzyme immunoassays. McAbs specific for IgA PAN (n= 24), IgA1 (n= 7), IgA2 (n= 3), IgA2m
(2)(n= 2), non-IgA2m (2)(n= 4) and SC or secretory IgA (n= 5) were identified that were …