Tumor necrosis factor-α (TNFα), a cytokine produced mainly by macrophages, is involved in
immunoregulation, the modulation of cell growth and differentiation, as well as in the
induction of oxygen free radicals. In preeclamptic placentas, lipid peroxides are increased
as compared to normal placentas. If TNFα was abnormally increased in preeclamptic
placentas, it might contribute to the increased oxidative stress and the formation of lipid
peroxides. We hypothesized that TNFα levels would be higher in preeclamptic than in …