The molecular biology of mammalian lipoxygenases and the quest for eicosanoid functions using lipoxygenase-deficient mice
CD Funk - Biochimica et Biophysica Acta (BBA)-Lipids and Lipid …, 1996 - Elsevier
Lipoxygenases are a family of non-heme iron-containing enzymes distributed widely
throughout the plant and animal kingdoms that stereospecifically insert molecular oxygen
into certain polyunsaturated fatty acids like linoleic acid and arachidonic acid. Crystalline
lipoxygenase was reported by Theorell as early as 1947 [1]. The first three-dimensional X-
ray crystal structure of a lipoxygenase (soybean isozyme-1) was reported in 1993 [2]. The
emergence of molecular biology techniques led to the first deduced primary structures of …
throughout the plant and animal kingdoms that stereospecifically insert molecular oxygen
into certain polyunsaturated fatty acids like linoleic acid and arachidonic acid. Crystalline
lipoxygenase was reported by Theorell as early as 1947 [1]. The first three-dimensional X-
ray crystal structure of a lipoxygenase (soybean isozyme-1) was reported in 1993 [2]. The
emergence of molecular biology techniques led to the first deduced primary structures of …