Production and characterization of monoclonal antibodies against the leukemia inhibitory factor low affinity receptor, gp190
V Pitard, JL Taupin, V Miossec, F Blanchard… - Journal of …, 1997 - Elsevier
Leukemia inhibitory factor (LIF), oncostatin-M (OSM), ciliary neurotrophic factor (CNTF) and
cardiotrophin-1 (CT1) act through transmembrane receptors which share the gp190
glycoprotein chain. The understanding of its involvement in the biology of these cytokines is
of importance since these systems have recently been shown to participate in major
inflammatory and neoplastic processes such as myelomatosis (Rose-John, S., Heinrich, PC,
1994. Soluble receptors for cytokines and growth factors: generation and biological function …
cardiotrophin-1 (CT1) act through transmembrane receptors which share the gp190
glycoprotein chain. The understanding of its involvement in the biology of these cytokines is
of importance since these systems have recently been shown to participate in major
inflammatory and neoplastic processes such as myelomatosis (Rose-John, S., Heinrich, PC,
1994. Soluble receptors for cytokines and growth factors: generation and biological function …