[CITATION][C] CD4+ cell turnover
DS Dimitrov, MA Martin - Nature, 1995 - nature.com
• •• • • •• •• • • Page 1 SCIENTIFIC CORRESPONDENCE 0.100 0 a b ~ • t A A .s 0.075 A .,,. A C,
A u A A 'o A ~ 0.050 •• ,~ 0.552 0. 0 l O.Q25 AA • ! AA • •• •• 0.000 0 100 200 300 ..., 500 600
0.5 Plasma viraemia exponential slope of "CD4 lymphocyte turnover" (0.004-0.088) shown in
Table 1 of ref. 1 is inconsistent with replacement of CD4 T cells solely by rapid cell division, as
the exponential slope should be relatively constant (reflecting mainly the relatively minor
variations in cell-cycle time). Examination of lymph nodes from both HIV-infected progressors4 …
A u A A 'o A ~ 0.050 •• ,~ 0.552 0. 0 l O.Q25 AA • ! AA • •• •• 0.000 0 100 200 300 ..., 500 600
0.5 Plasma viraemia exponential slope of "CD4 lymphocyte turnover" (0.004-0.088) shown in
Table 1 of ref. 1 is inconsistent with replacement of CD4 T cells solely by rapid cell division, as
the exponential slope should be relatively constant (reflecting mainly the relatively minor
variations in cell-cycle time). Examination of lymph nodes from both HIV-infected progressors4 …