New aspects on the role of plasma lipases in lipoprotein catabolism and atherosclerosis

U Beisiegel - Atherosclerosis, 1996 - Elsevier
The function of lipoprotein lipase (LpL) and hepatic lipase (HL) has been related to
atherogenesis by several authors in the past, but convincing experimental and
epidemiological evidence to support this hypothesis has been obtained only in the last
years. For both enzymes, next to their role in the hydrolysis of triglyceride-rich lipoproteins, a
second important function has been described recently. Both lipases can mediate the
binding and subsequent uptake of lipoproteins into cells. Although this function has been …