[HTML][HTML] Insulin-stimulated tyrosine phosphorylation of caveolin is specific for the differentiated adipocyte phenotype in 3T3-L1 cells
CC Mastick, AR Saltiel - Journal of Biological Chemistry, 1997 - ASBMB
Previous work from this laboratory has shown that insulin stimulates the tyrosine
phosphorylation of caveolin in 3T3-L1 adipocytes (Mastick, CC, Brady, MJ, and Saltiel, AR
(1995) J. Cell Biol. 129, 1523–1531). This phosphorylation is specific for insulin and
involves the activation of a tyrosine kinase downstream of the insulin receptor. We report
here that tyrosine phosphorylation of caveolin is detected only in fully differentiated
adipocytes, not in fibroblasts (preadipocytes), despite the fact that both cell types express …
phosphorylation of caveolin in 3T3-L1 adipocytes (Mastick, CC, Brady, MJ, and Saltiel, AR
(1995) J. Cell Biol. 129, 1523–1531). This phosphorylation is specific for insulin and
involves the activation of a tyrosine kinase downstream of the insulin receptor. We report
here that tyrosine phosphorylation of caveolin is detected only in fully differentiated
adipocytes, not in fibroblasts (preadipocytes), despite the fact that both cell types express …