Signal transduction through NF-κB
The inducible transcription factor NF-κB plays a central role in the regulation of many
immune and inflammatory responses. Advances in our knowledge of the signaling
mechanisms that control the activation of NF-κB and recent insights into the nature of the IκB-
kinase represent significant steps forward in understanding this important signaling
pathway.
immune and inflammatory responses. Advances in our knowledge of the signaling
mechanisms that control the activation of NF-κB and recent insights into the nature of the IκB-
kinase represent significant steps forward in understanding this important signaling
pathway.
Abstract
The inducible transcription factor NF-κB plays a central role in the regulation of many immune and inflammatory responses. Advances in our knowledge of the signaling mechanisms that control the activation of NF-κB and recent insights into the nature of the IκB-kinase represent significant steps forward in understanding this important signaling pathway.
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