Collectins: pattern recognition molecules involved in first line host defense
K Sastry, RA Ezekowitz - Current opinion in immunology, 1993 - Elsevier
K Sastry, RA Ezekowitz
Current opinion in immunology, 1993•ElsevierA group of chimeric molecules comprising globular heads, which contain the carbohydrate
recognition domain, and collagen tails are defined as Collectins. The mannose-binding
proteins, pulmonary surfactant apoproteins A and D and conglutinin all qualify as members
of this family, whose function appears to be as pattern recognition molecules involved in the
first line of defense in the pre-immune host.
recognition domain, and collagen tails are defined as Collectins. The mannose-binding
proteins, pulmonary surfactant apoproteins A and D and conglutinin all qualify as members
of this family, whose function appears to be as pattern recognition molecules involved in the
first line of defense in the pre-immune host.
Abstract
A group of chimeric molecules comprising globular heads, which contain the carbohydrate recognition domain, and collagen tails are defined as Collectins. The mannose-binding proteins, pulmonary surfactant apoproteins A and D and conglutinin all qualify as members of this family, whose function appears to be as pattern recognition molecules involved in the first line of defense in the pre-immune host.
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