Modification of enzymatically amplified DNA for the detection of point mutations.

A Haliassos, JC Chomel, L Tesson, M Baudis… - Nucleic Acids …, 1989 - ncbi.nlm.nih.gov
511 of the amplified samples were digestedwithMsp Page 1 Volume 17 Number 9 1989
Modifi'cation of enzymaticalHy amplified DNA for the detection of point mutations A.Haliassos,
JCChomel, L.Tesson, M.Baudis, J.Kruh, JCKaplan and A.Kitzis* , Institut de Pathologie
Moleculaire, CHU Cochin, 24 rue du Fbg St Jacques, F-75014, Paris, France Submitted April 4,
1989 The detection of geneticpolymorphisms1 or point mutations2,3, correlated with diseases, in
enzymatically amplified DNA sequences (Polymerase Chain Reaction), was performed by …