Human granulocytic ehrlichiosis in the upper Midwest United States: a new species emerging?

JS Bakken, JS Dumler, SM Chen, MR Eckman… - Jama, 1994 - jamanetwork.com
Objective.—To characterize the clinical presentation and course, laboratory findings, and
treatment outcome of 12 patients with human granulocytic ehrlichiosis. Setting.—The 12
patients were male, ranged in age from 29 to 91 years, and contracted their illness in
Wisconsin or Minnesota. Methods.—Cases were recognized by the presence of
intracytoplasmic inclusions (morulae) in peripheral neutrophils of patients presenting with
temperature of 38.5° C or higher, chills, severe headache, and myalgias. All patients had a …