Effect of chronic ethanol feeding on the hepatic secretion of very-low-density lipoproteins

S Venkatesan, RJ Ward, TJ Peters - … et Biophysica Acta (BBA)-Lipids and …, 1988 - Elsevier
Using Triton WR-1339 to inhibit plasma metabolism of VLDL, hepatic secretion of VLDL was
measured in vivo in control and alcohol-fed rats. The composition of VLDL secreted from
livers of chronically alcohol-fed rats was compared with pair-fed controls. The results show
that the cholesterol, esterified and nonesterified, as well as the triacylglycerol content of
VLDL secreted by the alcohol-fed rats was significantly reduced; protein and phospholipid
constituents of the VLDL were unaltered. The apoprotein components of the VLDL showed …