High density lipoprotein and lipoprotein oxidation

CL Banka - Current opinion in lipidology, 1996 - journals.lww.com
CL Banka
Current opinion in lipidology, 1996journals.lww.com
HDL protects LDL from oxidative damage known to contribute to the onset and progression
of atherosclerosis. This antioxidant protection by HDL is mediated by intrinsic hydrolytic
enzyme systems, by accelerated selective uptake of lipid peroxides from HDL and by
antioxidant molecules. Oxidative damage suffered by HDL as a result of the transfer of
reactive species from LDL may compromise HDL function in cholesterol transport.
Abstract
HDL protects LDL from oxidative damage known to contribute to the onset and progression of atherosclerosis. This antioxidant protection by HDL is mediated by intrinsic hydrolytic enzyme systems, by accelerated selective uptake of lipid peroxides from HDL and by antioxidant molecules. Oxidative damage suffered by HDL as a result of the transfer of reactive species from LDL may compromise HDL function in cholesterol transport.
Lippincott Williams & Wilkins