[HTML][HTML] Protein kinase C isozymes differentially regulate promoters containing PEA-3/12-O-tetradecanoylphorbol-13-acetate response element motifs

AE Reifel-Miller, DM Conarty, KM Valasek… - Journal of Biological …, 1996 - ASBMB
To investigate the regulation of promoters containing classical phorbol ester response
sequences (PEA-3/12-O-tetradecanoylphorbol-13-acetate response element motifs) by
protein kinase C (PKC) isozymes, co-transfections were performed in human dermal
fibroblasts with a plasmid containing either the human collagenase promoter or the porcine
urokinase plasminogen activator (uPA) promoter linked to the chloramphenicol
acetyltransferase gene and a plasmid expressing an individual PKC isozyme. Using this …