Monocyte chemotactic peptide-1 expression in acute and chronic human nephritides: a pathogenetic role in interstitial monocytes recruitment.
G Grandaliano, L Gesualdo, E Ranieri… - Journal of the …, 1996 - journals.lww.com
Tubulointerstitial damage is a common histopathological feature of acute and chronic renal
diseases and a prognostic indicator of renal function outcome. Monocytes infiltrating the
interstitium, through the release of cytokines and/or growth factors, may play a key role in the
pathogenesis of tubulointerstitial damage. Monocyte chemotactic peptide-1 (MCP-1) is a
specific and powerful chemoattractant and activating factor for monocytes. This study
investigated MCP-1 expression and its correlation with monocyte infiltration and …
diseases and a prognostic indicator of renal function outcome. Monocytes infiltrating the
interstitium, through the release of cytokines and/or growth factors, may play a key role in the
pathogenesis of tubulointerstitial damage. Monocyte chemotactic peptide-1 (MCP-1) is a
specific and powerful chemoattractant and activating factor for monocytes. This study
investigated MCP-1 expression and its correlation with monocyte infiltration and …