The Fanconi anaemia gene FANCF encodes a novel protein with homology to ROM
JP De Winter, MA Rooimans, L Van Der Weel… - Nature …, 2000 - nature.com
JP De Winter, MA Rooimans, L Van Der Weel, CGM Van Berkel, N Alon, L Bosnoyan-Collins…
Nature genetics, 2000•nature.comFanconi anaemia (FA) is a chromosomal instability syndrome with autosomal recessive
inheritance. We have identified the gene mutated in Fanconi anaemia group F patients by
complementation cloning. FANCF has no introns and encodes a polypeptide with homology
to the prokaryotic RNA binding protein ROM.
inheritance. We have identified the gene mutated in Fanconi anaemia group F patients by
complementation cloning. FANCF has no introns and encodes a polypeptide with homology
to the prokaryotic RNA binding protein ROM.
Abstract
Fanconi anaemia (FA) is a chromosomal instability syndrome with autosomal recessive inheritance. We have identified the gene mutated in Fanconi anaemia group F patients by complementation cloning. FANCF has no introns and encodes a polypeptide with homology to the prokaryotic RNA binding protein ROM.
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