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Zonulin-dependent loss of gut mucosal barrier and MIS-C
In this episode, the authors explain that in multisystem inflammatory syndrome in children (MIS-C), increased gastrointestinal mucosal permeability allows SARS-CoV-2 antigens in the GI tract to leak into the bloodstream...
Published July 15, 2021
Author's Take
Hemophilia A and immune response
In this episode, Valder Arruda explains that depletion of the cytokine B cell activating factor in hemophilia A may provide a way to prevent or eradicate factor VIII inhibitors...
Published July 9, 2021
Author's Take
Efficient maternal to neonatal transfer of antibodies
In this episode, Michal Kovo explains that antenatal BNT162b2 mRNA vaccination induces a robust maternal humoral response that effectively transfers to the fetus, supporting the role of vaccination during pregnancy...
Published July 1, 2021
Author's Take
JCI’s Conversations with Giants in Medicine: Jesse Roth, Ron Kahn, and Jeff Flier
We shift our format this month to bring you three giants in medicine, Dr. Jesse Roth of the Feinstein Institutes for Medical Research, Dr. C. Ronald Kahn of the Joslin Diabetes Center at Harvard Medical School, and Dr. Jeffrey Flier...
Published June 15, 2021
Conversations with Giants in Medicine
Immune checkpoint receptors for HBV infection
In this episode, Shie-Liang Hsieh and Tsung-Yu Tsai explain that HBV interacts with SIGLEC-3 and causes impairment of host immunity...
Published June 1, 2021
Author's Take
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