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AMP[K]-lifying view of the diabetic kidney
The presence of increased glucose levels in diabetes patients is considered to drive diabetes-associated complications, including retinopathy, neuropathy, and nephropathy. Cultured cells...
Published October 25, 2013
Scientific Show Stopper
Scratching the itch
Chronic itchiness is a symptom of many different skin diseases. The development of the itch sensation is triggered by sensory neurons and this signal is then transferred to the brain. G-coupled...
Published October 15, 2013
Scientific Show Stopper
Nerves in the gut
Hirschprung disease is the result of incomplete development of the enteric nervous system (ENS) within the bowel. The ENS is originates from enteric neural crest–derived cells, which proliferate...
Published October 15, 2013
Scientific Show Stopper
A pain in the back
Pain in the lower back can be caused by a variety of factors including overuse injury, aging, and arthritis. A major source of back pain is lumbar disc degeneration (LDD), which is characterized by...
Published October 8, 2013
Scientific Show Stopper
Regulating immune activation by necrotic cells
Researchers identify cellular mechanisms regulating cancer cell immunogenicity.
Published October 8, 2013
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