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Clinical Medicine

The Journal of Clinical Investigation wants to publish your research that has the potential to change the practice of medicine. Submissions of interest in the JCI's new Clinical Medicine category include reports of intervention trials, including Phase I or II trials, that provide an early demonstration of clinically relevant outcomes for new therapies and diagnostics, as well as reports of rigorous observational studies and meta-analyses.
“Through the years, the JCI has strived to publish articles that elucidate the mechanisms of human disease, but our connection to disease therapy, one of the tenets of the JCI’s founders, has become less direct. Indeed, the logical extension of our mission at the journal is to publish original research in humans that describes a new therapy for a disease. After all, we are the Journal of Clinical Investigation. Few journals have the ability to publish in the same issue a detailed mechanistic study in a model organism next to human research that advances a new therapy for a disease.”

— from JCI Editor in Chief Howard A. Rockman's December 2012 editorial

Recent Clinical Medicine articles

Key facts

  • Expertise. The JCI has expanded its Editorial Board to include editors devoted specifically to ensuring fast and fair review of Clinical Medicine submissions. More about the Clinical Medicine Associate Editors
  • Impact. The JCI's Impact Factor (12.812 in 2012) places it among the top 4 journals in the "Medicine, Research & Experimental" category.
  • Speed to decision. For submissions sent to external reviewers, authors can expect to receive decisions within 30 days on average. For submissions that the Board determines not to be of interest to the JCI, authors can expect to receive decisions within 7 days on average.
  • Exposure and audience. The JCI publishes a limited number of research articles each month — your work won't get lost in a long list. The JCI's readership includes members of the American Society for Clinical Investigation (ASCI), which owns and publishes the JCI, and the general public. The JCI makes all of its research available for free to the public and deposits all research into Pubmed Central.

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Submission guidelines

Create or access your JCI author account