The Journal of Clinical Investigation wants to publish your research that has the potential to change the practice of medicine. Submissions of interest in the JCI's new Clinical Medicine category include reports of intervention trials, including Phase I or II trials, that provide an early demonstration of clinically relevant outcomes for new therapies and diagnostics, as well as reports of rigorous observational studies and meta-analyses.
Through the years, the JCI has strived to publish articles that elucidate the mechanisms of human disease, but our connection to disease therapy, one of the tenets of the JCI’s founders, has become less direct. Indeed, the logical extension of our mission at the journal is to publish original research in humans that describes a new therapy for a disease. After all, we are the Journal of Clinical Investigation. Few journals have the ability to publish in the same issue a detailed mechanistic study in a model organism next to human research that advances a new therapy for a disease.”
— from JCI Editor in Chief Howard A. Rockman's December 2012 editorial
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