Submit a Letter to the Editor for:
Antonio Castrillo, Peter Tontonoz
J Clin Invest. 2004;
114(11):1538
doi:10.1172/JCI23705
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ardiovascular disease is the leading cause of morbidity and mortality in Western countries. Previous studies have highlighted the beneficial effects of PPARγ activators on cardiovascular disease; however, the role of other PPAR family members in atherosclerosis is less clear. A report in this issue of the JCI expands our understanding of PPARs in vascular biology and highlights the potential use of multiple PPAR agonists to limit lipid accumulation in macrophages.
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