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Sarah K. Bronson, Chad E.N. Reiter, Thomas W. Gardner
J Clin Invest. 2003;
111(12):1817
doi:10.1172/JCI18927
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iabetic retinopathy, the most frequent complication of diabetes and leading cause of vision loss, involves vascular and neural damage in the retina. Insulin and IGF-1 signaling are now shown to contribute to retinal neovascularization, in part, by modulating the expression of various vascular mediators.
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