Host cyclooxygenase-2 modulates carcinoma growth
J. Clin. Invest. Christopher S. Williams, et al. 105:1589 doi:10.1172/JCI9621 [
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Figure 5Decreased vascular density in LLC tumors when grown in
COX-2–/– mice. (
a) Representative photomicrographs of factor VIII–stained tumor sections from LLC tumors grown in wild-type (+/+) or
Ptgs2–/– (–/–) mice (×200). (
b) Factor VIII–positive vessel counts obtained by morphometric analysis of LLC tumors. Values represent the average number of vessels at ×200 ± the SD (Student’s
t test;
P = 0.04). HPF, high power field.
