Host cyclooxygenase-2 modulates carcinoma growth
J. Clin. Invest. Christopher S. Williams, et al. 105:1589 doi:10.1172/JCI9621 [
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Figure 4COX-2 and VEGF are expressed in LLC isografts.
COX-2 (upper panels,
a and
b, wild-type host),
VEGF (middle panels,
c and
d, wild-type host), and
VEGF (lower panels,
e and
f,
COX-2–/– host) riboprobes were hybridized to sections from tumors grown in C57BL/6 mice with the designated genotype (×400). Control hybridizations with sense cRNA riboprobes were performed to validate the specificity of Rnase-A–resistant hybrids. WT, wild-type.
