Host cyclooxygenase-2 modulates carcinoma growth
J. Clin. Invest. Christopher S. Williams, et al. 105:1589 doi:10.1172/JCI9621 [
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Figure 1Host-derived COX-2 is important for LLC tumor growth. (
a) A total of 2 × 10
6 LLC cells were implanted into
COX-2+/+ (gray bars),
COX-2+/– (white bars), or
COX-2–/– (black bars) C57BL/6 mice; (
b) a total of 2 × 10
6 LLC cells were implanted into
COX-1+/+ (gray bars) or
COX-1–/– (black bars) C57BL/6 mice. Tumor volumes were calculated from tumor measurements scored at the indicated day. Results are presented as the mean tumor volume ± SEM.
