In vivo alterations of IFN regulatory factor-1 and PIAS1 protein levels in cystic fibrosis epithelium
J. Clin. Invest. Thomas J. Kelley, et al. 106:403 doi:10.1172/JCI9560 [
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Figure 2NOS2-specific immunostaining in excised murine nasal epithelial tissue. Bright-field view of nasal epithelial tissue from wild-type C57BL/6J mice (
a) and
IRF-1–/– mice (
b). NOS2-specific fluorescent immunostaining from wild-type C57BL/6J mice (
c) and
IRF-1–/– mice (
d).
IRF-1–/– mice have a C57BL/6J background. Images are representative of results obtained with four mice of each genotype. Samples processed identically but not incubated with anti-NOS2 antibody showed no staining (data not shown). Objective images (×40).