Junctional communication of pancreatic β cells contributes to the control of insulin secretion and glucose tolerance
J. Clin. Invest. Anne Charollais, et al. 106:235 doi:10.1172/JCI9398 [Go to this article.]

Figure 2
Transgenic mice express Cx32 in pancreatic islets. (a) Antibodies against Cx32 immunostained this protein in acinar cells of exocrine pancreas (a), but failed to reveal it in endocrine cells of pancreatic islets (i). (c and d) In contrast, the same antibodies resulted in a punctate immunostaining of islet cells in both heterozygous (c) and homozygous (d) mice. Scale bar, 30 μm. (b) Islet immunostaining was about twice as high in homozygous (solid column) than in heterozygous (open column) animals. Data are mean ± SEM of the indicated number of islets.