Dominant and recessive inheritance of morbid obesity associated with melanocortin 4 receptor deficiency
J. Clin. Invest. I. Sadaf Farooqi, et al. 106:271 doi:10.1172/JCI9397 [Go to this article.]

Figure 2
Inheritance of mutations in MC4R. Cosegregation of mutational status with BMI is shown for the five families in the mutational screening study for whom family data were available. Also shown is the family tree for the family with the CTCT deletion reported previously by us (9). Filled symbols represent subjects with severe obesity. The first line of the symbols corresponds to the identification number. The second line shows the genotype: N, normal allele; M, mutant allele. The third and fourth lines show current age of subject (years) and BMI standard deviation score, respectively.