Dominant and recessive inheritance of morbid obesity associated with melanocortin 4 receptor deficiency
J. Clin. Invest. I. Sadaf Farooqi, et al. 106:271 doi:10.1172/JCI9397 [Go to this article.]

Figure 1
Sequence variants detected in MC4R. The positions of the sequence variants described in Table 1 are indicated on a model of the MC4R protein structure. Amino acids are indicated as circles in single-letter code. Amino acids affected by mutations are shaded, and specific mutations are then indicated in a shaded oval. Shaded ovals outlined in black indicate mutations where phenotypic studies on patients have been performed. Codon number 1 refers to the initiator methionine.