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Beckwith-Wiedemann syndrome: imprinting in clusters revisited
Eamonn R. Maher, Wolf Reik
Published in Volume 105, Issue 3
J Clin Invest. 2000; 105(3):247–252 doi:10.1172/JCI9340
This article Copyright © 2000, The American Society for Clinical Investigation
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Figure 1

The imprinting cluster on human chromosome 11p15.5. The distal breakpoint cluster region (BWSCR1) is indicated. Breakpoints within BWSCR1 disrupt KvLQT1. Solid red symbols indicate allelic silencing; green/white symbols indicate allelic transcription. The imprinting status of the INS (insulin) gene has not been defined in humans. Further details are included in the text.

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