A chemokine-to-cytokine-to-chemokine cascade critical in antiviral defense
J. Clin. Invest. Thais P. Salazar-Mather, et al. 105:985 doi:10.1172/JCI9232 [Go to this article.]

Figure 2
IFN-γ production in serum, spleen, and liver. Serum samples (a) and spleen (b) or liver (c) homogenates were prepared from uninfected or MCMV-infected (at 24, 36, and 48 hours after infection) MIP-1α⁺ or MIP-1α^– mice. IFN-γ protein was measured by ELISA. Each spleen homogenate data point consists of 6 animals tested individually. For liver homogenates, each uninfected and 24-hour data point consists of 6 animals, and each 36- and 48-hours data point consists of 9 animals, all tested individually. The means ± SE are shown. All samples from uninfected or 24-hour MCMV-infected mice were below the level of detection. Differences between MIP-1α⁺ and MIP-1α^– are significant, ^AP < 0.0005.