A chemokine-to-cytokine-to-chemokine cascade critical in antiviral defense
J. Clin. Invest. Thais P. Salazar-Mather, et al. 105:985 doi:10.1172/JCI9232 [Go to this article.]

Figure 1
Compartmental changes in NK cell populations. Blood (a and b) and liver (c and d) leukocytes were prepared from C57BL/6-MIP-1α⁺/⁺ (MIP-1α⁺) or C57BL/6-MIP-1α^–/– (MIP-1α^–) mice either uninfected or infected with MCMV for 48 hours. Leukocytes were analyzed by flow cytometry as described in Methods. Both the percentage (a and c) and absolute number (b and d) of NK1.1⁺CD3^– cells per milliliter of blood or NK1.1⁺TCR-β^– cells per entire liver are shown. Data are means ± SE (n = 3). Compartmental changes represent results from 1 of 3 repetitive experiments. Differences between control MIP-1α⁺ and MIP-1α^– are significant, ^AP < 0.01, ^BP < 0.001.