Attenuated hypoxic pulmonary hypertension in mice lacking the 5-hydroxytryptamine transporter gene
J. Clin. Invest. S. Eddahibi, et al. 105:1555 doi:10.1172/JCI8678 [Go to this article.]

Figure 6
Western blot of 5-HTT protein in lungs from 5-HTT^+/+ and 5-HTT^–/– mutant mice at the end of a 2-week exposure to normoxia or hypoxia. (a) The 5-HTT immunoreactivity in lungs from 5-HTT^+/+ mice (lanes 1, 3) and 5-HTT^–/– mice (lanes 2, 4). The specific antibodies recognized a protein with an apparent molecular weight of 64 kDa. (b) Quantitation of the 5-HTT signal in lungs from normoxic and chronically hypoxic 5-HTT^+/+ and 5-HTT^–/– mice (n = 5 in each group). ^AP < 0.05 as compared with 5-HTT levels in normoxic 5-HTT^+/+ mice.