Attenuated hypoxic pulmonary hypertension in mice lacking the 5-hydroxytryptamine transporter gene
J. Clin. Invest. S. Eddahibi, et al. 105:1555 doi:10.1172/JCI8678 [
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Figure 5Normalized wall thickness measured in fully muscular arteries in lungs from
5-HTT+/+ and
5-HTT–/– mice exposed to chronic hypoxia over 2 weeks (
n = 9 mice of each genotype) or 5 weeks (
n = 8 mice of each genotype).
AP < 0.05,
BP < 0.01 as compared with values in
5-HTT+/+ mice exposed to hypoxia of the same duration.
