Systemically derived large intestinal CD4⁺ Th2 cells play a central role in STAT6-mediated allergic diarrhea
J. Clin. Invest. Mi-Na Kweon, et al. 106:199 doi:10.1172/JCI8490 [Go to this article.]

Figure 4
Protection of OVA-induced diarrhea in STAT6^–/– mice. No sign of diarrhea or of eosinophil infiltration was observed in the large intestines of STAT6^–/– mice (a). Significantly lower levels of total or OVA-specific IgE Ab’s in serum (b) and of OVA-specific IgG and IgA AFCs in the large intestines (c) of STAT6^–/– mice (^–/–) were noted when compared with those of wild-type mice (+/+). ^AP < 0.01 versus wild-type mice.