Systemically derived large intestinal CD4⁺ Th2 cells play a central role in STAT6-mediated allergic diarrhea
J. Clin. Invest. Mi-Na Kweon, et al. 106:199 doi:10.1172/JCI8490 [Go to this article.]

Figure 1
Induction of Th2-mediated allergic diarrhea. Diarrhea was induced in systemically primed mice by oral challenge with 50 mg of OVA (a, closed circle). Control mice were orally challenged with 50 mg of OVA without any systemic priming (a, open circle). Eosinophils (b) and mast cells (c, right panel) selectively infiltrated into the large intestines of diarrhea-induced mice. However, control group (c, left) did not show the increase of mast cells. Arrows point to eosinophils. Original magnification, × 200–400.