Natural antibodies with the T15 idiotype may act in atherosclerosis, apoptotic clearance, and protective immunity
J. Clin. Invest. 105:12 doi:10.1172/JCI8472
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Figure 6

T15 IgA recognizes apoptotic cells. FACS® analysis of T15 Ab and control IgA (C-IgA; nonspecific monoclonal) binding to apoptotic PAECs. (a) Apoptosis-induced PAECs were gated into two populations according to PI intensity and FSC as described (7). Region 2 (R2): normal cells and cells in very early apoptosis. Region 1 (R1): cells with dim and bright PI staining (apoptotic). (b) Binding of control IgA and T15 to R2 cells. (c) Binding of control IgA and T15 to R1 cells.