Targeted expression of a dominant-negative EGF-R in the kidney reduces tubulo-interstitial lesions after renal injury
J. Clin. Invest. Fabiola Terzi, et al. 106:225 doi:10.1172/JCI8315 [
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Figure 3Morphology of sham-operated (
a and
b) and remnant kidneys (
c and
d) from wild-type (
a and
c) and transgenic (
b and
d) mice, 8 months after surgery. Nephron reduction induced several morphological changes of proximal tubules (compare
c with
a and
b), which were prevented by transgene expression (compare
d with
c). PAS staining, ×200.