Stable mixed chimerism and tolerance using a nonmyeloablative preparative regimen in a large-animal model
J. Clin. Invest. Christene A. Huang, et al. 105:173 doi:10.1172/JCI7913 [
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Figure 6Thymic regeneration and mixed chimerism establishment after nonmyeloablative preparative regimen. (
a) FACS dot plot representation of different size (FSC) fractions of (1) immature (CD1
+); (2) mature (CD3
+); and (3) donor-type (PAA
+) thymocytes before and 72 days after PBSCT in animal 13235. (
b) Two-color FACS analysis of thymocytes from animal 13235 on day 72 showing donor PAA+ thymocytes present in both the immature (CD1
+) and mature (CD3
+) fractions.
