Decreased neointimal formation in Mac-1–/– mice reveals a role for inflammation in vascular repair after angioplasty
J. Clin. Invest. Daniel I. Simon, et al. 105:293 doi:10.1172/JCI7811 [
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Figure 5Neutrophil adhesion to and transmigration across platelets. Microtiter wells or Transwell insert membranes were coated either with fibrinogen and platelets or with the indicated extracellular matrix proteins alone, as described in Methods. Bar graphs show adhesion (
a) and KC-stimulated transmigration (
b) of bone marrow–derived neutrophils from
Mac-1+/+ mice (solid bars) and
Mac-1–/– mice (open bars). Values are mean ± SD of 3–5 separate experiments. *
P = 0.002. **
P = 0.047. FGN, fibrinogen; FN, fibronectin.