Stephen, the proband who kindled my interest in genetic disorders. Reprinted, with permission from Excerpta Medica Inc. (Rowley, P.T., Mueller, P.S., Watkin, D.M., and Rosenberg, L.E. 1961. Familial growth retardation, renal aminoaciduria, and cor pulmonale. I. Description of a new syndrome with case reports. Am. J. Med. 31:187–204.)