Microchimerism of maternal origin persists into adult life
J. Clin. Invest. Sean Maloney, et al. 104:41 doi:10.1172/JCI6611 [
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Figure 1HLA-B44–specific PCR of DNA extracted from PBMCs of a 49-year-old scleroderma patient who was B44-negative and whose mother was B44-positive. Lanes 3 and 5 are patient samples from 2 different draw dates. Lane 7 is a positive control from the mother, and lane 8 is a positive control from a homozygous cell line. The patient’s HLA-B alleles were
B*0801 and
B*3508, and lanes 10 and 11 are negative controls derived from homozygous cell lines with these alleles. Lane 12 is a negative reagent control, and lanes 2, 4, 6, and 9 are blank.
