J Clin Invest.
Morphology of peripheral blood and bone marrow cells from Smap1–/– mice.
Smear samples were stained by May-Grunwald Giemsa. (A–F) In peripheral blood (PB), the cells are (A) polychromatic erythrocytes (arrows), (B) Howell-Jolly bodies (arrows), (C) erythroblasts (arrows), (D) giant platelets (arrow), (E) micromegakaryocytes (arrow), and (F) hypersegmented neutrophils (arrow). (G–K) In bone marrow cells (BM), the abnormal cells include (G) megaloblasts (arrow) and binucleated basophilic erythroblasts (arrowheads), (H) basophilic erythroblasts with cytoplasmic blebs (arrowheads) and pseudo-Pelger-Huet neutrophils (arrow), (I) multinucleated polychromatic megaloblasts, (J) orthochromatic erythroblasts with fragmented nuclei (arrows), and (K) megakaryocytes with hypolobulated nuclei. Scale bar: 10 μm.