Impaired physiological responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1α
J. Clin. Invest. Aimee Y. Yu, et al. 103:691 doi:10.1172/JCI5912 [
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Figure 5Pulmonary histology. Lungs from
Hif1a+/+ (
a and
c) and
Hif1a+/+ (
b and
d) mice exposed to 21% (
a and
b) or 10% (
c and
d)
O for 3 weeks were formalin-fixed, paraffin-embedded, sectioned, and stained with hematoxylin and eosin for videomicroscopy. Each field shows a representative pulmonary arteriole. ×400.