Impaired physiological responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1α
J. Clin. Invest. Aimee Y. Yu, et al. 103:691 doi:10.1172/JCI5912 [
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Figure 4Right ventricular pressures of normoxic, hypoxic, and reoxygenated mice. Mean right ventricular (
RV) pressure (± SE) was determined for
Hif1a+/+ (
open bars) and
Hif1a+/– (
closed bars) mice exposed to 21% (
n = 6) or 10% (
n = 11–15)
O for 3 weeks, or exposed to 10%
O for 3 weeks followed by 21%
O for 3 h (
n = 5). *
P = 0.003;
#P = NS (Student's
t test).
NS, not significant.
