Hepatocyte growth factor leads to recovery from alcohol-induced fatty liver in rats
J. Clin. Invest. Minoru Tahara, et al. 103:313 doi:10.1172/JCI4433 [
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Figure 3Effects of HGF on serum lipid concentrations and hepatic apoB mRNA levels of rats. Changes in serum lipid concentrations (
a) (
n = 6), lipid compositions in lipoproteins (
b) (
n = 6), and hepatic apoB mRNA levels (
c) (
n = 4) are shown. Rats were fed ethanol diets for 37 days, and hrHGF or saline alone was daily injected for the last 7 days during 37 days. (
c) Total RNA was dot–blotted to nylon membranes and hybridizes with cDNA for apoB and GAPDH, as described in Methods. In
a and
c, each value represents the mean ± SD In
b, mean values are represented. *
P < 0.05, **
P < 0.01 vs. saline control.
GAPDH, glyceraldehyde-3-phosphate dehydrogenase.
