Hepatocyte growth factor leads to recovery from alcohol-induced fatty liver in rats
J. Clin. Invest. Minoru Tahara, et al. 103:313 doi:10.1172/JCI4433 [Go to this article.]

Figure 1
HGF-induced changes in hepatic lipid contents in rats with alcoholic fatty liver. Rats were pair-fed isocaloric liquid diets for 30 days (n = 4), or ethanol-containing diets for 30 days (n = 4) or 37 days. hrHGF (n = 6) or saline (n = 6) alone was daily injected for the last 7 days during a 37-day treatment with ethanol diets. Each value represents the mean ± SD. ^#P < 0.05, ^##P < 0.01 ethanol-fed rats vs. pair-fed rats; *P < 0.05, **P < 0.01 HGF-treated rats vs. saline control. HGF, hepatocyte growth factor; hrHGF, human recombinant hepatocyte growth factor.