(A) Appearance of mesenteric and omental fat in control mice. (B) Decreased adiposity in JAK2L mice. The enlarged, pale, yellow liver is also visible. (C) Percent body fat as determined by DXA scanning in control and JAK2L mice (n = 5 for each group). (D) Epididymal fat pad weight of control and JAK2L mice (n = 5 for each group). Male mice were used exclusively in the experiments in this figure. Values are expressed as mean ± SEM. *P < 0.05, ***P < 0.001.